Molecular Barcoded Plasmid Yeast ORF Library: Linking Bioactive Compounds to their Cellular Targets and Mapping Dosage Suppressor Networks
In this thesis I describe a functional genomics resource in which each yeast gene, with its native promoter and 3’UTR, is cloned on a uniquely barcoded low-copy vector. We refer to this resource as the Molecular Barcoded Yeast ORF (MoBY-ORF) library 1.0. Each gene carried by MoBY-ORF 1.0 should mim...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/29745 |