Genomic Rearrangements in Human and Mouse and their Contribution to the Williams-Beuren Syndrome Phenotype
Genomic rearrangements, particularly deletions and duplications, are known to cause many genetic disorders. The chromosome 7q11.23 region in humans is prone to recurrent chromosomal rearrangement, due to the presence of low copy repeats that promote non-allelic homologous recombination. The most w...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/26341 |