Hexokinase 2 is a Key Mediator of Aerobic Glycolysis Promoting Tumour Growth in Glioblastoma Multiforme

Proliferating tissues, including embryonic and tumour tissues, preferentially employ aerobic glycolysis to support cell growth. This reliance on glycolysis even in the presence of oxygen, referred to as the “Warburg Effect”, may confer a proliferative, survival and invasive advantage and be exploite...

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Bibliographic Details
Main Author: Wolf, Amparo
Other Authors: Guha, Abhijit
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/26339