Hexokinase 2 is a Key Mediator of Aerobic Glycolysis Promoting Tumour Growth in Glioblastoma Multiforme
Proliferating tissues, including embryonic and tumour tissues, preferentially employ aerobic glycolysis to support cell growth. This reliance on glycolysis even in the presence of oxygen, referred to as the “Warburg Effect”, may confer a proliferative, survival and invasive advantage and be exploite...
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Language: | en_ca |
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2010
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Online Access: | http://hdl.handle.net/1807/26339 |