Synthesis of Aromatic Heterocycles and Carbocycles Through Tandem Palladium-catalyzed Cross-couplings of gem-dihaloolefins

Our group has developed a strategy for the synthesis of benzofused carbocycles and heterocycles through tandem palladium-catalyzed reactions of gem-dibromoolefins. In these syntheses, one bromide undergoes a Pd-catalyzed cyclization reaction, and the other participates in an orthogonal inter- or int...

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Bibliographic Details
Main Author: Bryan, Christopher
Other Authors: Lautens, Mark
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/26133