The In vivo effects of Rac1 and Rac2 on Bone Quality and Aging

Introduction: The Rho family of small GTPases, including Rac1 and Rac2, are key regulators of osteoclast differentiation and function; however, little is known about their roles in bone quality and aging. Methods: Male four and nine month old mice (n=10) with Rac1, Rac2 or both (DKO) isoforms del...

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Bibliographic Details
Main Author: Thang, Herman
Other Authors: Grynpas, Marc D.
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/25823