Wnt Signaling in Human Neural Stem Cells and Brain Tumour Stem Cells
We sought to determine whether activation of the Wnt signaling pathway altered the function of hNSCs in vitro. We took three approaches to activate Wnt signaling: Wnt3a, constitutively stabilized β-catenin (ΔN90), and the GSK3 inhibitor BIO. While Wnt3a and ΔN90 had no effect on proliferation in bot...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/25435 |