A Peptide Comprising the Src-interacting Domain of NADH Dehydrogenase Subunit 2 Alleviates Complete Freund's Adjuvant-induced Allodynia in Rats

Inflammatory and neuropathic pains arise in part from sensitization at nociceptive synapses in the spinal cord. Activity-dependent signaling cascades converge onto the tyrosine kinase Src, which participates in augmenting the function of N-methyl-D-aspartate receptors (NMDARs) and thus potentiates t...

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Bibliographic Details
Main Author: Barszczyk, Andrew
Other Authors: Tymianski, Michael
Language:en_ca
Published: 2010
Subjects:
Src
Online Access:http://hdl.handle.net/1807/25421