Hepatocyte Molecular Cytotoxic Mechanism Study of Fructose and its Metabolites Involved in Nonalcoholic Steatohepatitis and Hyperoxaluria
High chronic fructose consumption is linked to a nonalcoholic steatohepatitis (NASH) type of hepatotoxicity. Oxalate is the major endpoint of fructose metabolism, which accumulates in the kidney causing renal stone disease. Both diseases are life-threatening if not treated. Our objective was to stud...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/24568 |