Modulating Hedgehog Signaling can Attenuate the Severity of Osteoarthritis
Osteoarthritis is associated with the irreversible degeneration of articular cartilage. Notably, in this condition, articular cartilage chondrocytes undergo phenotypic and gene expression changes that are reminiscent of their end-stage differentiation in the growth plate during skeletal development....
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/24362 |