G-Protein Coupled Receptor Mediated Metaplasticity at the Hippocampal CA1 Synapse

Activity of the NMDA receptor is crucial for CA1 plasticity. Functional modification of the receptor is one way to modulate synaptic plasticity and affect hippocampus dependent behaviours. Two GPCRs, the dopamine receptor D1 and the PACAP38 receptor PAC1, have been shown to enhance NMDA activity via...

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Bibliographic Details
Main Author: Sidhu, Bikrampal Singh
Other Authors: MacDonald, John F.
Language:en_ca
Published: 2009
Subjects:
CA1
LTP
Online Access:http://hdl.handle.net/1807/19093