Health Technology Assessment of Thiopurine Methyltransferase Testing for Guiding 6-Mercaptopurine Doses in Pediatric Patients with Acute Lymphoblastic Leukemia

This study determined whether phenotype or genotype tests for thiopurine methyltransferase (TPMT) are cost effective interventions for guiding doses of 6-mercaptopurine in children with acute lymphoblastic leukemia (ALL) compared to standard weight-based dosing. A systematic review of the literatur...

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Bibliographic Details
Main Author: Donnan, Jennifer
Other Authors: Ungar, Wendy Joan
Language:en_ca
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1807/18282