Central Nervous System (CNS) Nutrient Sensing in Diabetes

An acute increase in hypothalamic glucose and its downstream metabolite lactate lower glucose production (GP) and plasma glucose (PG) levels in normal rodents. However, the effectiveness of this nutrient-sensing mechanism in metabolic disease is unknown. We assessed the effects of intracerebroventri...

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Bibliographic Details
Main Author: Chari, Madhu
Other Authors: Lam, Tony K. T.
Language:en_ca
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1807/18251