Analysis of Naked in the Canonical Wnt Pathway

Wnt signalling is involved throughout development and is inappropriately activated in a variety of human cancers. In the canonical pathway, secreted Wnt proteins induce the stabilization of b-catenin. Drosophila Naked (Nkd), or Nkd1 and Nkd2 in vertebrates, is believed to antagonize canonical Wnt si...

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Bibliographic Details
Main Author: Lau, Garnet Jean
Other Authors: Attisano, Liliana
Format: Others
Language:en_ca
Published: 2008
Subjects:
Wnt
Online Access:http://hdl.handle.net/1807/17191