A Novel Model System is Applied to Examine the Interplay of Notch and GATA Factors during T Lineage Committment

T lymphocytes comprise one arm of the adaptive immune system and are critical for immunity to neoplasia and infection. A full understanding of their development has important implications for the treatment of autoimmunity, immunodeficiency, and leukemias arising from T cell developmental intermediat...

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Bibliographic Details
Main Author: de Pooter, Renee
Other Authors: Zuniga-Pflucker, Juan Carlos
Format: Others
Language:en_ca
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/1807/16774