Inducing Cellular Senescence in Cancer
Cellular senescence is a permanent cell cycle arrest that is induced as a response to cellular stress. Replicative senescence is a well-described mechanism that limits the replicative capacity of cells and must be overcome by cancer cells. Oncogene-induced senescence (OIS) is a form of premature sen...
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Language: | en |
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2013
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Online Access: | http://hdl.handle.net/10393/23691 |