Pou5f1 Post-translational Modifications Modulate Gene Expression and Cell Fate

Pou5f1 Post-translational Modifications Modulate Gene Expression and Cell Fate

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Embryonic stem cells (ESCs) are characterized by their unlimited capacity for self-renewal and the ability to contribute to every lineage of the developing embryo. The promoters of developmentally regulated loci within these cells are marked by coincident epigenetic modifications of gene activation...

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Bibliographic Details
Main Author: Campbell, Pearl
Language:en
Published: 2012
Subjects:
Oct4
pluripotency
stem cells
Akt
Polycomb Group Proteins
Trithorax Group Proteins
transcriptional regulation
transcriptional regulatory network
cancer
cell cycle checkpoint function
cell fate transitions
cell cycle
SET complex
Hmgb2
post-translational modifications
Pou5f1
Signal Transduction
embryonic stem cells
Set
Online Access:http://hdl.handle.net/10393/23607

Internet

http://hdl.handle.net/10393/23607

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