Identification of Novel Roles for the Survival Motor Neuron (Smn) Protein: Implications on Spinal Muscular Atrophy (SMA) Pathogenesis and Therapy

Identification of Novel Roles for the Survival Motor Neuron (Smn) Protein: Implications on Spinal Muscular Atrophy (SMA) Pathogenesis and Therapy

Show other versions (2)

Spinal muscular atrophy (SMA) is the leading genetic cause of death of young children. It is an autosomal recessive disease caused by the mutation and/or the deletion within the ubiquitously expressed survival motor neuron 1 (SMN1) gene. SMA pathology is characterized by spinal cord motor neuron d...

Full description

Bibliographic Details
Main Author: Bowerman, Melissa
Language:en
Published: 2012
Subjects:
spinal muscular atrophy
survival motor neuron protein
actin cytoskeletal dynamics
Rho GTPases
motor neuron
skeletal muscle
neuromuscular junctions
Rho-kinase inhibitors
glucose metabolism
pancreatic islet
profilin
plastin 3
Online Access:http://hdl.handle.net/10393/22727

Internet

http://hdl.handle.net/10393/22727

Similar Items