Biochemical and Functional Characterization of Novel RNA-binding Proteins Interacting with SMN in Motor Neuron-derived Cells

Spinal muscular atrophy is an autosomal recessive genetic disease that results from the loss and/or degeneration of alpha motor neurons in the lower part of the spinal cord. With ~ 1 in 6000 live births per year being affected, this disease is the second leading cause of infant death and is caused b...

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Bibliographic Details
Main Author: Laframboise, Janik
Language:en
Published: 2013
Subjects:
HuD
SMN
Online Access:http://hdl.handle.net/10393/23656