Efforts Toward an Oxa-conjugate Addition Based Approach to (+)-Neopeltolide Synthesis
(+)-Neopeltolide is a highly potent marine polyketide natural product with activity against multiple cancer cell lines in vitro. The nanomolar range of antifungal and anticancer cytotoxicity in this tetrahydropyran (THP)-containing polyketide, combined with its limited natural supply, has led to se...
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| Language: | en |
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2012
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| Online Access: | http://hdl.handle.net/10393/23125 |