The Role of CD8+ T Cell Phenotype and Cytotoxicity on Cancer Immunotherapy
Cancer vaccines can fail despite the induction of large numbers of CD8+ T cells. Two categories of memory CD8+ T cells have been defined; central memory (TCM, IL-7RαhighCD44highCD62Lhigh) and effector memory (TEM, IL-7RαhighCD44highCD62Llow). It is clear that the memory phenotype of CD8+ T cells ca...
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| Language: | en |
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2011
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| Online Access: | http://hdl.handle.net/10393/20278 |