Construction of a Synthetic Human VL Phage Display Library and Isolation of Potential Neuropilin-1-specific VL Therapeutics from the Library

Antibody phage display technology mimics the natural immune system, and has been widely used for rapid isolation of single-domain antibodies (sdAbs) with various binding specificities and affinities in the micromolar to low nanomolar range. SdAbs are the variable regions of immunoglobulins (e.g., V...

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Bibliographic Details
Main Author: Keklikian, Artine
Language:en
Published: 2011
Subjects:
VL
Online Access:http://hdl.handle.net/10393/20197