Deregulation of the Transcriptional Repressor E2F6 in Myocardium Leads to Gene Activation and Dilated Cardiomyopathy
The E2F family of transcription factors regulate cellular growth, death and differentiation, but their role in cardiac biology remains to be fully explored. We hypothesized that the balance of the E2F pathway would determine cardiac development and function. We provide evidence for this via modulati...
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| Language: | en |
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2011
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| Online Access: | http://hdl.handle.net/10393/19964 |