The effects of 1,4-benzoquinone on c-Myb and topoisomerase II in K-562 cells

Exposure to benzene, a ubiquitous environmental pollutant, has been linked to leukemogenesis, although the mechanism of benzene initiated carcinogenesis remains unclear. It has been proposed that benzene can be bioactivated to toxic metabolites such as 1,4 benzoquinone (BQ), which can alter signalli...

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Bibliographic Details
Main Author: Singh, Roopam
Other Authors: Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))
Format: Others
Language:en
en
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/1974/972