Post-Weaning Social Isolation and Subchronic NMDA Glutamate Receptor Blockade: Effects on Locomotor Activity and GABA Signalling in the Rat

The etiology and pathophysiology of schizophrenia are poorly understood, although increasing evidence suggests an important role for altered GABA neurotransmission. Animal models of schizophrenic symptoms include administration of noncompetitive N-methyl-D-aspartate (NMDA) glutamate receptor antagon...

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Bibliographic Details
Main Author: Hickey, Andrea
Other Authors: Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))
Language:en
en
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1974/6013