INHIBITION OF PHOSPHATIDYLINOSITOL 3-KINASE (PI3K) SIGNALLING LEADS TO RESISTANCE TO CHEMOTHERAPEUTIC AGENTS IN HUMAN CANCER CELLS

One of the major challenges associated with cancer therapy is the acquisition of chemoresistance by tumour cells. Many novel therapeutic approaches to overcome chemoresistance have involved targeting specific signalling pathways such as the phosphatidylinositol 3-kinase (PI3K) pathway, a stress res...

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Bibliographic Details
Main Author: Mcdonald, GAIL
Other Authors: Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))
Format: Others
Language:en
en
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/1974/1475