Long-term heme synthesis inhibition: vascular implications
Heme is essential for numerous enzymes involved in the regulation of vascular tone; it is an integral component of nitric oxide synthase and soluble guanylyl cyclase, and is the substrate for heme oxygenase, enzymes critical for vasodilation. Inhibition of heme synthesis is anticipated to result in...
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| Format: | Others |
| Language: | en en |
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2008
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| Online Access: | http://hdl.handle.net/1974/1263 |