Role of the Breast Cancer Susceptibility 2 BRC Repeats in Homologous Recombination
Homologous recombination (HR) is a faithful mechanism for the repair of double-stranded DNA breaks (DSBs) and plays a critical role in maintaining the integrity of genomic DNA. The product of the Breast Cancer Susceptibility 2 (BRCA2) gene functions as a recombination mediator in HR-directed repair...
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| Language: | en |
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2012
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| Online Access: | http://hdl.handle.net/10214/5259 |