The In Silico Search for an Endogenous Anti-Alzheimer's Therapeutic
Alzheimer’s disease (AD) is a progressive, degenerative neurological disorder for which there is no cure. The causative agent is ?-amyloid (A?) which becomes neurotoxic upon conformational change from ?-helix to ?-sheet. In silico methods have been used to indentify endogenous small molecules of the...
Main Author: | |
---|---|
Language: | en |
Published: |
2011
|
Subjects: | |
Online Access: | http://hdl.handle.net/10222/14390 |