Precursor-Directed Biosynthesis of Novel Jadomycins and Expansion of the Jadomycin Library

Jadomycins are secondary metabolites produced by Streptomyces venezuelae ISP5230 VS1099 in response to conditions of stress such as heat or ethanol shock. They have been shown to exhibit antibiotic and anticancer activity. Unique structural features of the jadomycins include a rare 2,6-dideoxysuga...

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Bibliographic Details
Main Author: Dupuis, Stephanie
Language:en
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10222/13053