The carboxyl-terminal extension on DNA polymerase a of Saccharomyces cerevisiae is required for mitochondrial DNA maintenance at 37C
The mitochondrial DNA (mtDNA) polymerase of 'Saccharomyces ', Mip1p, contains a unique carboxyl-terminal extension (CTE) that extends about 300 amino acids past the last conserved motif in the polymerase domain. To analyze the function of the CTE, we created mutant cell lines expressing v...
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Format: | Others |
Language: | en en_US |
Published: |
2007
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Online Access: | http://hdl.handle.net/1993/2543 |