Characterization of growth, apoptosis, and differentiation of CHO and human erythroleukemic K562 cells exposed to dexrazoxane, and the selection of a dexrazoxane-resistant K562 cell line
The bisdioxopiperazines including dexrazoxane are strong catalytic inhibitors of DNA topoisomerase II. The aim of the following study was to examine the ' in vitro' effects of dexrazoxane on the growth, cytotoxicity, morphology, cell cycle progression, and where applicable induction of ap...
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| Format: | Others |
| Language: | en en_US |
| Published: |
2007
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| Online Access: | http://hdl.handle.net/1993/2267 |