Identification of non-essential host genes required for PrP106-126 mediated neurotoxicity
Prion diseases are invariably fatal proteinaceous neurodegenerative disorders of the central nervous system. The infectious agent is the host encoded prion protein which has undergone a post-translational refolding from a predominantly alpha-helical to highly beta-sheet containing structure. The m...
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2011
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| Online Access: | http://hdl.handle.net/1993/4801 |