Solubility and Conformational Studies of the Intrinsically Disordered HIV-1 Tat1-72 Protein
Tat1-72, is an intrinsically disordered protein at pH 4.1 as previously indicated by NMR chemical shifts and coupling constants, and confirmed by 15N-relaxation parameters. The presence of SDS elicits a conformational change to α-helicity in Tat1-72. In the presence of the non-ionic DDM detergent...
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| Language: | en_US |
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2011
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| Online Access: | http://hdl.handle.net/1993/4594 |