APOPTIN AND ITS DERIVATIVES AS MOLECULAR CLUES TOWARDS THE DEVELOPMENT OF NOVEL TYROSINE KINASE INHIBITORS
The non-receptor tyrosine kinase activity of fusion gene BCR-ABL derived oncoproteins is the key factor responsible for development and progress of Philadelphia positive (Ph+) chronic myeloid leukemia (CML). In the search for a superior and novel peptide-based inhibitor of Bcr-Abl, here I investigat...
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| Language: | en_US |
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2009
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| Online Access: | http://hdl.handle.net/1993/3188 |