Microfluidics-assisted investigation of T-lymphocyte Migration in lymph node relevant chemokine gradients

Microfluidics-assisted investigation of T-lymphocyte Migration in lymph node relevant chemokine gradients

T-lymphocytes (T-cells) trafficking in the lymph nodes (LNs) is key for T-cells activation and their effector functions in adaptive immune responses. T-cells enter the LNs through high endothelial venules (HEVs) and interact with dendritic cells (DCs) for cognate antigens in the T-cell zone (TCZ)....

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Bibliographic Details
Main Author: ANDALUR NANDAGOPAL, Saravanan
Other Authors: Lin, Francis (Physics and Astronomy) Levin, David (Biosystems Engineering)
Published: PLoS ONE 2014
Subjects:
Microfluidics
T-lymphocyte
Immune cell
Lymph node
Online Access:http://hdl.handle.net/1993/23247

Internet

http://hdl.handle.net/1993/23247

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