Regulation of extracellular adenosine levels, role of nucleoside transporters, purine metabolism and the blood-brain-barrier

Adenosine is an important neuromodulator in brain and, through activation of membrane bound receptors, it has been reported to have neuroprotective properties during strokes or seizures. The levels of adenosine have been reported to increase up to 100-fold during cerebral ischemia; however, the pat...

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Bibliographic Details
Main Author: Sinclair, Christopher J. D.
Language:en_US
Published: 2007
Online Access:http://hdl.handle.net/1993/1937