B-adrenoceptor signal transduction in high-output heart failure due to aortocaval shunt in rat

B-adrenoceptor signal transduction in high-output heart failure due to aortocaval shunt in rat

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The failing heart is characterized by blunted B-adrenoceptor (B-AR) responses associated with a number of changes in the signal transduction pathway including downregulation of B-ARs, increased expression of inhibitory G-proteins and G-protein coupled receptor kinases (GRKs) and impaired adenylyl c...

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Bibliographic Details
Main Author:	Wang, Xi
Language:	en_US
Published:	2007
Online Access:	http://hdl.handle.net/1993/1929

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