B-adrenoceptor signal transduction in high-output heart failure due to aortocaval shunt in rat
The failing heart is characterized by blunted B-adrenoceptor (B-AR) responses associated with a number of changes in the signal transduction pathway including downregulation of B-ARs, increased expression of inhibitory G-proteins and G-protein coupled receptor kinases (GRKs) and impaired adenylyl c...
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| Language: | en_US |
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2007
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| Online Access: | http://hdl.handle.net/1993/1929 |