Myogenic and functional effects of deflazacort therapy on mdx dystrophic mice
Duchenne muscular dystrophy (DMD) is caused by a lack of dystrophin. ' Mdx' dystrophic mice experience acute and extensive muscle fiber necrosis at 3wks-of-age, followed by regeneration with little disability. Early treatment with deflazacort, a glucocorticoid, slows dystrophy and improves...
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| Language: | en_US |
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2007
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| Online Access: | http://hdl.handle.net/1993/1826 |