The role(s) of JLP scaffolding protein in regulating LPS- vs. poly(I:C)-activated mature dendritic cell functions

TLR3- and TLR4-mediated DC activation lead to distinct function of mature DC, in which MAPKs pathway is involved. JNK-associated leucine zipper protein (JLP) associates with JNK/p38 phosphorylation, however the role of JLP in DC is not well understood. We previously found either LPS or poly(I:C) up-...

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Bibliographic Details
Main Author: Zhao, Chongbo
Other Authors: Kung, Sam (Immunology)
Published: 2012
Subjects:
JLP
Online Access:http://hdl.handle.net/1993/14165