Loading of doxorubicin into liposomes by forming Mn2+ drug complexes

Loading of doxorubicin into liposomes by forming Mn2+ drug complexes

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Doxorubicin has been encapsulated into liposomes with a transmembrane pH gradient. In this thesis, a new procedure for loading doxorubicin into large unilamellar vesicles (LUVs) is characterized and compared to loading using the ionophore A23187 with MnSO₄ containing liposomes. It is shown that d...

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Bibliographic Details
Main Author:	Cheung, Chung-Ling
Language:	English
Published:	2009
Online Access:	http://hdl.handle.net/2429/8037

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