Loading of doxorubicin into liposomes by forming Mn2+ drug complexes
Doxorubicin has been encapsulated into liposomes with a transmembrane pH gradient. In this thesis, a new procedure for loading doxorubicin into large unilamellar vesicles (LUVs) is characterized and compared to loading using the ionophore A23187 with MnSO₄ containing liposomes. It is shown that d...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
2009
|
| Online Access: | http://hdl.handle.net/2429/8037 |