Induction of valproic acid metabolism in rat liver microsomes by carbamazepine and carbamazepine-10, 11-epoxide
Vaiproic acid (VPA) is a commonly used anticonvulsant agent that is often given in combination with carbamazepine (CBZ) to maximize seizure control. The incidence of VPA associated hepatotoxicity is increased when coadministered with other anticonvulsants. One or more of VPAs metabolites may be...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
2009
|
| Online Access: | http://hdl.handle.net/2429/7004 |