In vitro modulation of classic II MHC antigen expression by human cerebral endothelium and endothelial cell-lymphocyte interactions by interferons [gamma] and [beta]

In autoimmune demyelinating disorders of the central nervous system (CNS), the blood-brain-barrier (BBB) becomes permeable to plasma proteins and circulating leukocytes. Studies on Multiple Sclerosis (MS) suggest the involvement of T4⁺ lymphocytes and Ia⁺ macrophages in lesion extension and demye...

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Bibliographic Details
Main Author: Huynh, Hanh Kim
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/6921