The effect of transcription factor YY1 and small molecules on HIV-1 expression

Current therapies to treat patients infected with HIV-1 do not represent a cure. The virus persists as a latent chromosomally integrated provirus in unstimulated helper T-cells that is unaffected by current drugs and can become reactivated upon stimulation of the T-cell receptor. Much research is cu...

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Bibliographic Details
Main Author: Bernhard, Wendy
Language:English
Published: University of British Columbia 2014
Online Access:http://hdl.handle.net/2429/46610