Biochemical characterization and regulation of transcription of Polycomb Group RING Finger 5

The Polycomb Group (PcG) is a highly conserved group of genes which serve to repress transcription via specific modifications of histones in chromatin. The PcG has well-established roles in development and is involved, by mutation or dysregulation, in many human diseases including cancer. This stu...

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Bibliographic Details
Main Author: Cochrane, Christopher Larson
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/44991