Molecular targeting of polo-like kinase 1 (PLK1) for the treatment of brain tumours

Brain cancer is a disease that is difficult to treat and has a high mortality rate. Two of the major challenges facing current treatments are disease relapse and drug resistance. Disease relapse may be attributable to brain tumour initiating cells (BTICs), which are multi-potent stem-like cells en...

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Bibliographic Details
Main Author: Lee, Cathy
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/44820