Developmental consequences of imprinted transcription at the Mest locus
The Mest locus is regulated by genomic imprinting in mammals and only the paternally inherited allele is expressed. A targeted mutation at this locus revealed that it plays an important role in the regulation of embryonic growth and adult behavior. The Mest locus is located in a conserved imprinted...
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Language: | English |
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University of British Columbia
2013
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Online Access: | http://hdl.handle.net/2429/44537 |