Structural and functional studies of GlcNAc-modified Tau
O-GlcNAcylation is an abundant post-translational modification found on serine and threonine hydroxyl groups of nucleocytoplasmic proteins. O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA) are the sole enzymes responsible for addition and removal of all GlcNAc moieties, respectively. Although O-GlcN...
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| Language: | English |
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University of British Columbia
2013
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| Online Access: | http://hdl.handle.net/2429/44270 |