Role of somatostatin receptors in epidermal growth factor mediated EGFR signaling in breast cancer and human embryonic kidney 293 cells

Epidermal growth factor receptor (ErbB1) and somatostatin receptors (SSTRs) exert opposing effects on tumor promoting signaling pathways. Whether SSTRs functionally interact with ErbB1 and modulate tumor-promoting signaling is currently unknown. For this reason, the specific emphasis of this thesis...

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Bibliographic Details
Main Author: Kharmate, Geetanjali
Language:English
Published: University of British Columbia 2012
Online Access:http://hdl.handle.net/2429/41991